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Drug Delivery Model


In this work, MATLAB is used to simulate the delivery of a novel nanoparticle chemotherapy drug to cancerous tissue. Simulation allows scientists to predict experimental outcomes and thus reduce the cost of development and time to clinical relevance. The movies below show the initial proliferation of a cluster of tumor cells before death once the drug is administered. The simulation model includes blood vessels, tumor cells, and healthy cells and an engine to calculate the spatial distributions of both drug and oxygen. Jacket is used to speed up the diffusion calculations for the drug and oxygen within the tissue.

Authors: MIBLAB at the Georgia Institute of Technology. Center for Cancer Nanotechnology Excellence at Georgia Tech and Emory
Speedup: 70X
System Specs: MATLAB R2008A, an NVIDIA Tesla C870 GPU, and an Intel E2180 CPU


Drug Delivery Videos

Simulation of Cancer Cell Response to Drug Delivery.

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(Last Updated: 09 November 2008)



Diffusion Profile of Drug Delivery.

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(Last Updated: 09 November 2008)



Tissue Oxygenation Profile.

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(Last Updated: 09 November 2008)


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